This session discusses the latest omics technologies — spanning genomics, transcriptomics, proteomics, and metabolomics, including modeling and in silico approaches — to decipher the complex regulatory mechanisms of Pseudomonas species. The ultimate goal is to translate this research into applications across healthcare, environment, sustainability, and biotechnology while showcasing the genetic diversity, metabolic capabilities, and collective behavior (e.g. quorum sensing and biofilm formation) of the genus through selected case studies.
This session evaluates current and emerging approaches to explore antimicrobial tolerance mechanisms in Pseudomonas spp. The efficacy of existing treatments, multi-resistant strain challenges, and the transition of innovations from research to clinical (both human and veterinary) and agricultural practice will be fully addressed, emphasizing regulatory and trial obstacles. Innovative drug development strategies and cutting-edge fundamental research will be showcased, discussing the integration of effective therapeutic integration and commonly used approaches to combat Pseudomonas infections.
By exploring the dynamics of Pseudomonas infections across biological kingdoms, this session will highlight bacterial adaptability and its role in disease mechanisms. We will delve into the ecological significance of Pseudomonas in the context of different interaction scenarios. Comparing defense mechanisms across humans, animals, plants, and marine life will underscore the need for innovative diagnostics and therapeutics, advocating for cross-disciplinary collaboration and sustainable approaches in understanding and managing Pseudomonas infections.
This session explores the metabolic and physiological traits of Pseudomonas species underlying the remarkable adaptability and versatility of the genus. We will learn about the diverse metabolic pathways and regulatory mechanisms that both allow Pseudomonas to thrive in various environments and underscore the use of Pseudomonas species in bioremediation and biotechnology.
Delving into the rational engineering of Pseudomonas species towards multiple applications, this session focuses on their potential for the production of chemicals, biopolymers, and enzymes. The session will highlight contemporary synthetic biology and metabolic engineering strategies to either enhance the natural capacity of Pseudomonas as a microbial cell factory or to bestow completely new-to-nature traits of industrial interest. Along with the latest developments in the field, we will discuss the challenges of scaling-up, regulatory frameworks, and ensuring economic and environmental sustainability.
Aiming to unravel the evolutionary trajectories of Pseudomonas species in different scenarios, this session will discuss the genetic and ecological mechanisms shaping their diversity and adaptability. These aspects cover horizontal gene transfer, mutation profiles, selection pressures, and coevolutionary relationships with hosts, competitors, and predators — offering insights into microbial interactions in both natural and laboratory conditions, with a focus on the ability of Pseudomonas spp. to thrive in changing environments.
This session emphasizes the contribution of Pseudomonas to sustainability and environmental health by investigating the ecological roles of the genus. Agriculture, bioremediation, and biocontrol capabilities will be used as examples to discuss how Pseudomonas spp. support sustainability approaches. By highlighting symbiotic relationships in the rhizosphere and leveraging these for agriculture and soil health, the session will offer insights into harnessing Pseudomonas for environmental applications and sustainable practices.
Disentangling the complex web of interactions involving Pseudomonas species, this session stresses the ecological, evolutionary, and biotechnological implications of microbial interactions across kingdoms and environments. We will learn about symbiotic, antagonistic, and competitive dynamics with plants, animals, microbes, and fungi, analyzing their roles in ecosystem dynamics and microbial communities. The examples discussed in this session will deepen our appreciation for the inherent complexity of microbial lifestyles — and how to harness them for several applications.