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X-WR-TIMEZONE:Europe/London
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CLASS:PUBLIC
BEGIN:VEVENT
DTSTART:20221122T115500
DTEND:20221122T122000
DTSTAMP:20260509T164949Z
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SUMMARY:TBC
DESCRIPTION:Bacteria and archaea have developed multiple antiviral mechanisms, and genomic evidence indicates that several of these antiviral systems co-occur in the same strain. Here, we introduce DefenseFinder, a tool that automatically detects known antiviral systems in prokaryotic genomes. We use DefenseFinder to analyse 21000 fully sequenced prokaryotic genomes, and find that antiviral strategies vary drastically between phyla, species and strains. Variations in composition of antiviral systems correlate with genome size, viral threat, and lifestyle traits. DefenseFinder will facilitate large-scale genomic analysis of antiviral defense systems and the study of host-virus interactions in prokaryotes.
PRIORITY:1
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