Multi-scale approaches to understand multi-faceted biofilm challenges

Liam Rooney (University of Glasgow, UK)

15:45 - 16:00 Monday 13 April Morning

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Abstract

I joined the Department of Bacteriology at the University of Glasgow School of Infection and Immunity as a Fellow in April 2025, establishing an independent lab exploring how the spatial organisation of microbes shapes complex infections. My research integrates advanced optical microscopy – from multi-modal systems to low-cost printed microscopes – with microbiology and multi-omics approaches to study microbes across scales, from single cells to chronic biofilms.  My career began with a BSc in Cell and Molecular Biology at Glasgow Caledonian University, a brief time in industry, followed by a PhD at the University of Strathclyde, where I developed quantitative imaging methods to study biofilm architecture, bacterial motility, and microbial soil ecology. Postdoctoral roles at Heriot-Watt University and the University of Strathclyde extended into super-resolution microscopy and open-hardware development. This produced the first fully 3D-printed microscope and new lens fabrication methods using consumer-grade 3D printers. Alongside these posts, I led independent projects and collaborations across Europe and the USA, leading to several key studies and commendations, including Scottish Microscopist of the Year (2023) and the Infection Science Award (2025). My current research focuses on cross-scale infection imaging, clinical biofilm research, and accessible imaging technologies that democratise high-performance microscopy and diagnostics. These strands support efforts to understand resource trafficking in biofilms, host-microbe interactions in infection, targeted antimicrobial strategies, and low-cost optical hardware.  I also contribute to strengthening the microbiology and microscopy communities through leadership roles in the Royal Microscopical Society, conference organisation, public engagement, and co-organising the UK’s largest microscopy training course, SOMC.

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