In 2023, I used the word holobiont in the House of Lords. It marks the first - and so far only - use of the term recorded in Hansard. With the term microbiotoxicity, it was 2025, and much the same. Scientific knowledge of our bodies, and of the more-than-human world, have transformed the basis of our understanding of health in the past quarter century, but politics and policy have not even begun to catch up. On the issue of antimicrobial resistance there is a little more understanding; there is no excuse for there not to be, given Sir Alexander Fleming referred to it in his Nobel acceptance speech in 1945. But knowledge, and even genuine concern, as expressed by then UK Prime Minister David Cameron in 2014, in a speech prompted by Dame Sally Davies, has not translated into anything like adequate action. That action cannot just be on protecting antibiotics and anitiviral medicines, as crucial as that is, it has to come from a One Health perspective, acknowledging that the way we live threatens all of our futures. Factory farming cannot continue. Biocides cannot be added unnecessarily to products for the purposes of advertising promotion and windfall profits. We have to acknowledge the need to prevent diseases with publlic health measures rather than simply assuming we can find a pill to cure them. And we need to get far more people from scientific backgrounds into politics and policy. Continuing ignorance and avoidance will be catastrophic.