The genetic diversity of Candida albicans is fundamental to understanding its physiology, virulence, and response to antifungal treatments. However, the field currently still lacks a joint, comprehensive global resource that broadly captures this diversity. To address this gap, the Berman and Ralser laboratories have collaborated in an ERC Synergy project term 'Fungal Tolerance' to build an extensive collection of over 1800+ C. albicans strains sourced globally. The strains come from different decades, environments, infections niches, are associated to different outcomes or commensalism, and for many we have extensive metadata. We systematically isogenized these strains, sequenced their genomes, conducted extensive phenotypic characterization, quantified antifungal drug resistance and tolerance, and profiled their proteomes using mass spectrometry. Utilizing this unprecedented dataset, we are dissecting the mechanistic distinctions between drug resistance and drug tolerance in C. albicans. Importantly, we will soon release this comprehensive resource publicly available, empowering the scientific community to significantly advance research into this clinically critical fungal pathogen.