Symposium 61: Signals, Switches, Regulons and Cascades: Control of Bacterial Gene Expression
26 April 2002 publication
Edited by D. A. Hodgson and C. M. Thomas.
Published April 2002 by Cambridge University Press.
DNA sequencing has provided a wealth of information on the genetic material stored in bacterial genomes. The use of DNA arrays and proteomics will transform the scale of our ability to describe the patterns of gene expression as bacteria respond to their environments. However, the ability to control bacteria in a clinical context or exploit them in industrial or environmental contexts also depends on understanding the regulatory mechanisms that connect input experience to output response at the genetic level. This volume deals with our current knowledge of the circuits and networks that govern bacterial gene expression – from the single gene to the whole genome – providing the framework for explaining data from the post-genomics revolution.