Meet the Sir Howard Dalton Young Microbiologist of the Year Finalists: Alix Lee

Posted on September 15, 2022   by Microbiology Society

The Sir Howard Dalton Young Microbiologist of the Year Prize is awarded by the Society each year. The prize recognises and rewards excellence in science communication by a Microbiology Society member who is a postgraduate student or postdoctoral researcher, having gained their PhD in the last two years.

Finalists shortlisted from oral and poster presentations at Annual Conference 2022 will present their research at the Society Showcase on the 5th of October. In the run up to the event, we will be meeting the finalists and getting to know a bit about each of them and their work.

organic-shapes.jpg

Alix Lee: Second year PhD student at Wellcome-Wolfson Institute for Experimental Medicine at Queen’s University Belfast, UK

Alix Lee in body.jpg
© Alix Lee
What is the title of your talk?

Uncovering a Type VI Secretion System Molecular Switch That Governs the Horizontal Gene Transfer of Antimicrobial Resistance Genes, and Virulence Gene Dissemination​

What are your current research interests?

Bacteria-bacteria interactions, antimicrobial resistance gene and virulence factor dissemination, and infectious disease. My current research is focused on establishing the role of the Type VI Secretion System in the dissemination of antimicrobial resistance genes and virulence factors in Klebsiella pneumoniae.

How would you explain your research to a GCSE student?

Bacteria-bacteria interactions allow sharing of genetic material between different bacteria, such as antimicrobial resistance genes and virulence factors. This leads to emergence of multidrug resistance and hypervirulent bacteria, causing untreatable infections in healthy individuals. Bacteria can fight each other using a needle complex, known as the Type VI Secretion System (T6SS), to gain competitive advantage in their environment. My research aims to establish the role of the T6SS in the dissemination of antimicrobial resistance genes and virulence factors in Klebsiella pneumoniae – a bacteria responsible for causing pneumoniae and sepsis, amongst other diseases.

If you weren’t a microbiologist what would you be?

Looking after rescue dogs and helping them get adopted.