Reflections on the United Nations High-Level Meeting on Antimicrobial Resistance

Posted on October 25, 2024   by Will Thompson

Last month, the Microbiology Society attended the recent United Nations High-Level Meeting on Antimicrobial Resistance (UN HLM on AMR). In this blog, we highlight how this meeting marks a major step forward in establishing practical steps to addressing AMR. However, some commitments fall short and may be insufficient to drive global change.

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Last month, the Microbiology Society attended the recent United Nations High-Level Meeting on Antimicrobial Resistance (UN HLM on AMR). Convened by the President of the General Assembly, the meeting included representatives from UN Member States, the Quadripartite organisations (Food and Agriculture Organization of the United Nations, United Nations Environment Programme, World Health Organization, and World Organisation for Animal Health), the Global Leaders Group on Antimicrobial Resistance, government officials, industry players, and civil society [1]. The meeting was a critical opportunity for world leaders to come together and commit to clear, new targets and practical steps to tackle AMR [2].

The UN HLM on AMR represented a major step forward in establishing practical steps to addressing AMR. The various commitments are outlined in the Political Declaration, a formal document officially adopted by UN Member States during the HLM [1].

Highlights include:

  • Setting up an independent panel to provide evidence on AMR: The Quadripartite organisations have been invited to setup an independent panel by 2025, with a goal to provide evidence that supports Member States in tackling AMR. We would expect this panel to be modelled on the success of the Intergovernmental Panel on Climate Change (IPCC), the UN body for assessing the science related to climate change. Lessons from the IPCC “highlight the importance of legitimacy, independence, timely reporting, and cost-efficiency” [5]. 
  • The introduction of targets to tackle AMR:
    • Reducing global deaths associated with bacterial AMR by 10% by 2030. 
    • Supporting national action plans on AMR with a funding target of US$ 100 million, aiming for at least 60% of countries to have funded plans by 2030.
    • Increasing the global use of 'Access group antibiotics' to at least 70% by 2030.
    • Achieving basic Water, Sanitation and Hygiene (WASH) in all healthcare facilities and meeting WHO’s minimum requirements for Infection Prevention and Control (IPC) in 90% of countries by 2030.

While the introduction of targets is promising, some of the commitments fall short due to a lack of ambition. For example, the funding target of US$ 100 million by 2030 to support national action plans on AMR, pales in comparison to the funding of other urgent global challenges, such as the global HIV response (US$ 8.2 billion in 2023) and action against climate change (US$ 100 billion a year in 2024) [3]. This is despite AMR being attributed to significantly more deaths than HIV and calling for similar large-scale practice and system changes as action against climate change [3].

Moreover, a clear financing roadmap has not been laid out, which leaves behind developing countries that are disproportionately affected by AMR [4]. This funding shortfall therefore threatens to worsen global inequality and progress towards achieving many of the SDGs [4]. Additionally, the commitments are also insufficient to drive global change, including softer targets, ensuring equitable access to antibiotics and phasing out antibiotics for growth promotion in animals [4].

Holding policymakers to account is crucial as we work towards tackling AMR collaboratively and across sectors. Unfortunately, the Political Declaration establishes few mechanisms to hold stakeholders accountable and ensure they meet targets. This is particularly concerning given the ambition of some targets, such as a 10% reduction in AMR-related deaths. The next UN HLM on AMR has been scheduled for 2029, despite calls to hold the meeting in 2027 [3]. Considering the 2030 deadline for this target and several others, committing to a 2027 UN HLM would have been more appropriate to ensure progress remains on track.

Conclusion

The Microbiology Society celebrates the level of international exposure and attention AMR has received as a result of the UN HLM. We also welcome the progress made in terms of establishing practical steps to tackling AMR. Moving forward, we urge Member States to build on the momentum generated by UN HLM and strengthen their commitments to tackling AMR. However, without clear leadership and strong accountability, stakeholders may fail to follow-through on their commitments. The UN HLM has demonstrated political will to tackle AMR, but this needs to be followed through with concrete action to ensure real progress.

References

  1. United Nations. Political Declaration of the High-level Meeting on Antimicrobial Resistance; 2024. https://www.un.org/pga/wp-content/uploads/sites/108/2024/09/FINAL-Text-AMR-to-PGA.pdf [accessed 22 October 2024]
  2. Quadripartite Joint Secretariat On AMR. UNGA High-Level Meeting on AMR; 2024. https://www.qjsamr.org/about-us/unga-high-level-meeting-on-amr [accessed 22 October 2024]
  3. ReAct. Latest version of UN High-Level Meeting Political Declaration disappoints in crucial places; 2024. https://www.reactgroup.org/news-and-views/news-and-opinions/year-2024/latest-version-of-un-high-level-meeting-political-declaration-disappoints-in-crucial-places/ [accessed 22 October 2024]
  4. ReAct. ReAct statement on the final version of the Political Declaration on AMR; 2024. https://www.reactgroup.org/news-and-views/news-and-opinions/year-2024/react-statement-on-the-final-political-declaration-on-amr/ [accessed 22 October 2024]
  5. Ruckert A, Bishop J, JP Poirier M. Designing an Independent Panel on Evidence for Action against AMR; 2024. https://www.globalstrategylab.org/wp-content/uploads/2024/06/GSLPolicyBrief_IPEA-2024-06-13.pdf [accessed 22 October 2024]